What are the differences between THC and THCV?
THC (tetrahydrocannabinol) and THCV (tetrahydrocannabivarin) are two types of cannabinoid found in the cannabis plant. Although they share a similar chemical structure, their effects on the body are distinct.
Psychic effect: THC is the main psychoactive compound in cannabis, responsible for the euphoric or "high" associated with its use. It binds to CB1 receptors in the endocannabinoid system, which can lead to changes in perception, mood, behavior and consciousness.
THCV, on the other hand, is a little more complex. At low doses, it acts as a CB1 receptor antagonist, i.e. it blocks these receptors and attenuates the effects of THC. Consequently, at low doses, THCV produces no noticeable psychoactive effect. At higher doses, however, it can act as a CB1 receptor agonist, producing psychoactive effects.
Physiological effects: The two cannabinoids also have different potential therapeutic effects. THC has been used to treat a number of conditions, including chronic pain, nausea and vomiting associated with chemotherapy, and is also used to stimulate appetite in people with certain diseases.
THCV, meanwhile, is being studied for its potentially beneficial properties in regulating blood sugar levels, which could be useful for people with diabetes. It has also been suggested that it may help reduce appetite, which could be beneficial for weight management.
Presence in the cannabis plant: THC is the most common cannabinoid in the cannabis plant, while THCV is generally present in smaller quantities. However, certain strains of cannabis are specifically bred to produce higher levels of THCV.
These differences make THC and THCV unique compounds with a wide range of potential effects.